Searchable abstracts of presentations at key conferences in endocrinology

ea0003p75 | Cytokines and Growth Factors | BES2002

Ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon: Importance of P-selectin, CXC chemokines

Riaz A , Wan M , Dawson P , Jeppsson B , Thorlacius H

IntroductionLeukocyte recruitment is a key feature in (I/R)-induced tissue injury. We have developed and validated a novel method to study molecular mechanisms of leukocyte-endothelium interactions in the colonic microcirculation in vivo by use of inverted intravital fluorescence microscopy.Methods & ResultsIn male C57/BL6 mice the superior mesenteric artery was occluded 30 min and leukocyte rolling and ...